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Fertility Treatments
Personalized Fertility Planning in Istanbul
Fertility treatment is highly personal and often time-sensitive. Mapa Health supports international patients by helping organize the case review, clinic coordination, travel timing, and the practical steps around treatment in Istanbul.
Our fertility services include Standard IVF, Mild Stimulation IVF, IVF with ICSI, and IVF with PGT — each with personalized coordination, clinic matching, and full support throughout the treatment process.
Why Istanbul Is a Leading Destination for IVF and Fertility Care
Turkey hosts more than 160 licensed IVF centers and performs over 150,000 IVF cycles annually, ranking among the top destinations for fertility medical tourism in Europe and the MENA region. Package prices are 50–70% lower than the United Kingdom, Germany or the United States, while laboratory equipment and embryology protocols align with ESHRE and ASRM guidelines — time-lapse embryo incubators (EmbryoScope+, Geri), CAPA-IVM systems, and NGS-based PGT platforms from Illumina and Thermo Fisher.
Mapa Health partners only with Turkish Ministry of Health-licensed IVF centers whose annual cycle volume exceeds 1,000 cases and whose published ongoing pregnancy rates match or exceed European SART/ESHRE benchmarks. Every plan starts with a free hormone-panel review and returns a written protocol recommendation within 48 hours.
Compare IVF Protocols: Standard vs Mild vs ICSI vs PGT
Protocol choice depends on ovarian reserve, male factor, genetic history and prior cycle outcomes. Side-by-side:
| Protocol | Indication | Stimulation | Typical Egg Yield | Best For |
|---|---|---|---|---|
| Standard IVF | First-line IVF, normal ovarian reserve | Antagonist, 1500–3000 IU FSH | 8–15 oocytes | Age <38, AMH 1.2–3.5 |
| Mild IVF | Poor responders, PCOS, patient preference | Clomiphene/letrozole + 500–1000 IU FSH | 4–8 oocytes | High OHSS risk, low-budget cycles |
| IVF + ICSI | Male factor, prior fertilization failure | Any protocol + ICSI fertilization | Same as stimulation protocol | Low sperm count/motility, TESE/TESA sperm |
| IVF + PGT | Advanced maternal age, RPL, RIF, genetic disease | Standard IVF + ICSI + blastocyst biopsy | Need 2+ euploid embryos (~40% euploidy at 38+) | >38, recurrent pregnancy loss, carriers |
Ovarian Reserve & Fertility Assessment
Before planning a cycle, ovarian reserve is evaluated with three complementary tests:
- AMH (Anti-Müllerian Hormone): serum marker of remaining ovarian reserve. Normal 1.2–3.5 ng/mL. Low AMH (<1.0) suggests reduced response; very high AMH (>4.0) suggests PCOS with OHSS risk.
- AFC (Antral Follicle Count): transvaginal ultrasound on cycle day 2-3 counts antral follicles (2–10 mm). Normal total 10–30; <7 is considered diminished.
- Day-3 FSH & estradiol: baseline FSH >10 IU/L suggests diminished reserve. Estradiol >80 pg/mL on day 3 masks FSH and requires recheck.
- Semen analysis: WHO 2021 criteria: volume >1.4 mL, concentration >16 M/mL, motility >42%, normal morphology >4%. Any abnormality prompts ICSI.
IVF Success Rates by Age (SART/ESHRE)
Live birth per embryo transfer decreases with maternal age — the single strongest predictor. Approximate rates at top-tier centers:
- ✔Under 35: 45–55% live birth per blastocyst transfer (fresh or frozen).
- ✔35–37: 35–45%.
- ✔38–40: 25–35% — PGT-A increasingly recommended.
- ✔41–42: 15–20% per transfer.
- ✔43+: 5–10% with own eggs. Egg donation may be considered.
Pre-Cycle Workup: What to Send Before Travel
- ✔Hormone panel — AMH, FSH, LH, E2, TSH, prolactin (within 6 months).
- ✔Recent pelvic ultrasound with antral follicle count.
- ✔Infectious disease screen — HIV, HBV, HCV, syphilis, rubella immunity.
- ✔Semen analysis per WHO 2021 criteria.
- ✔Karyotype & carrier screening if PGT is planned.
What's Included in a Mapa Health IVF Package
Clinical Procedure
- ✔ Reproductive endocrinologist consultation
- ✔ Full baseline hormone panel + ultrasound
- ✔ Gonadotropin medication (Gonal-F / Puregon / Menopur)
- ✔ Monitoring ultrasounds + bloods
- ✔ Egg retrieval under sedation
- ✔ ICSI, EmbryoScope culture to blastocyst
- ✔ Single blastocyst transfer + vitrification of extras
- ✔ PGT-A biopsy + NGS analysis (optional)
Travel & Stay
- ✔ VIP airport – clinic – hotel transfers
- ✔ 5-star hotel for 12–15 nights (full cycle)
- ✔ Multi-lingual patient coordinator
- ✔ Psychological support referral
- ✔ Shared electronic health record
- ✔ 12-month follow-up (through pregnancy confirmation)
For detailed pricing per protocol, visit our IVF cost in Turkey page.
Why Choose Mapa Health for Your IVF Cycle in Istanbul
Mapa Health is a medical concierge that vets Istanbul's IVF centers against strict criteria: Turkish Ministry of Health license, reproductive endocrinology board certification, annual cycle volume >1,000, ESHRE-equivalent embryology standards, published pregnancy rates, and ASRM / ESHRE protocol alignment. We coordinate the full journey, return a written protocol recommendation before you commit, and stay reachable in your language through pregnancy confirmation.
- ✔Fixed all-inclusive price — medications, monitoring, egg retrieval, ICSI, embryo culture and transfer bundled.
- ✔Time-lapse embryology (EmbryoScope+ / Geri) with undisturbed embryo culture.
- ✔NGS-based PGT-A / PGT-M / PGT-SR through accredited reference labs.
- ✔Single embryo transfer (SET) policy — reduces twins and prematurity risk.
- ✔12-month tele-support through first-trimester pregnancy care.
Ready for a protocol recommendation? Request a free fertility review — most written protocols return within 48 hours.
Important Planning Notes
Fertility care is highly individualized, and the correct pathway depends on age, ovarian reserve, sperm analysis, prior treatment history, and timing.
- ⚠ Cycle planning requires recent fertility test results whenever possible
- ⚠ Travel dates often depend on medication timing and monitoring needs
- ⚠ Treatment options may change after doctor review and ultrasound findings
- ⚠ Laboratory planning and embryo development timelines vary by case
The most efficient fertility journeys start with a case review so the clinic can prepare the right plan before arrival in Istanbul.
How the Pathway Usually Works
Before travel
Previous IVF reports, hormone tests, and fertility history are reviewed.
Cycle planning
Doctors confirm the protocol, medication timeline, and the expected stay in Istanbul.
Treatment phase
Monitoring, retrieval, laboratory work, and transfer are carried out according to the personalized plan.
After treatment
Patients receive follow-up guidance and next-step recommendations.
Who May Benefit From This Category?
✔Good Candidates
- Patients exploring IVF-based fertility treatment options
- Those who already have hormone tests, sperm analysis, or prior cycle information
- International patients needing help organizing treatment travel
- Couples or individuals looking for coordinated fertility planning in Istanbul
✖Not Recommended For
- Patients expecting a final protocol without medical review
- Those unable to align treatment timing with the fertility cycle
- Anyone seeking guarantees before diagnostic assessment
- Patients unwilling to share prior fertility history or reports
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Health Counseling
Our multilingual consultants are available to assist you during business hours
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Affordable 5 star hotel accommodation
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Complimentary transfers between airport, clinic and hotel
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Exclusive city tours and cultural experiences arranged for group visitors
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Treatments performed in modern, fully-equipped medical facilities
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We serve patients from more than 20 countries worldwide
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From your initial consultation to your safe return home, our dedicated team ensures a seamless experience at every stage of your journey. We are committed to making you feel comfortable, supported, and cared for, just like at home.
